![]() To deliver the dose to the tumor, brachytherapy applicators are required to move the radiation isotopes into the body. Hence, it has the advantage of delivering high-dose treatment to the tumor while also protecting the organs at risk (OAR) around the tumor. Most of the radiation sources used in brachytherapy are radiation isotopes that emit low-energy gamma rays. In brachytherapy, the radiation sources are temporarily or permanently placed inside or nearby the tumor. Depending on the location of these radiation sources, radiation therapy is divided into external beam radiation therapy (EBRT) and brachytherapy. These include electromagnetic waves, e.g., gamma and X-rays, and particle radiation, such as electron, proton, carbon ion, and neutron beam treatment. Presently, various types of radiation treatments are used to treat cancers. KeywordsBrachytherapy, Radioisotope, Three-dimensional imaging, Image guidance, Intensity modulation Intensity-modulated brachytherapy is anticipated to be performed in the near future, and it is anticipated that the treatment outcomes of applicable cancers will be greatly improved by this treatment’s excellent dose delivery characteristics. Three-dimensional images, such as ultrasound, computed tomography, magnetic resonance imaging, and positron emission tomography are used for accurate delineation of treatment targets and normal organs. Recently, advanced treatment techniques used in EBRT, such as image guidance and intensity modulation techniques, have been applied to brachytherapy. As radioisotopes have high radioactivity and miniature size, the application of brachytherapy has expanded to high-dose-rate brachytherapy. Over time, however, various radioisotopes have been artificially produced. In the early 1900s, the radioisotopes used for brachytherapy were only radium or radon isotopes extracted from nature. Brachytherapy has a long history of more than 100 years. Because these isotopes can be positioned inside or near the tumor, it is possible to protect other organs around the tumor while delivering an extremely high-dose of treatment to the tumor. In brachytherapy, in contrast to EBRT, the radiation source is radioisotopes. Two of three patients with EP reservoirs had significant preradiation problems consisting of penile/pelvic pain requiring pain medications.Brachytherapy, along with external beam radiation therapy (EBRT), is an essential and effective radiation treatment process. ![]() ![]() The patient with the scrotal pouch reservoir did not experience side effects. Pre-existing urinary incontinence was unchanged. Patients (n = 4) with PV PP reservoirs received the highest mean doses of radiation to reservoirs and experienced mild prostatitis requiring treatment with alpha blockers. No patient reported a change in the functionality of the PP at the 1-month follow-up visit. We noted that the percent increase in mean AUA scores was worse in the intact group at 1 month postradiation however, no further intervention was required. One month postradiation, the scores were 11 and 8, respectively. The mean preradiation AUA scores were 5 and 4.8 for intact vs nonintact prostate patients, respectively. The mean dose to the penile bulb/crus was 1,640 cGy. The mean dose to the reservoirs was 1,684 cGy (PV: 2,457 cGy EP: 653 cGy). RESULTS: All seven patients completed their planned course of radiotherapy (RT) without any treatment interruptions. We retrospectively reviewed their experience, evaluating reservoir location (extraperitoneal vs paravesical ), radiation dose to implant components, preradiation and postradiation American Urological Association (AUA) scores, and penile implant functionality preradiation and postradiation. METHODS: Seven patients with PC and PPs received definitive (2 pts) or salvage radiation (5 pts) at two US Department of Veterans Affairs facilities. ![]() We will describe treatment experiences of seven patients with existing PP implants who were irradiated for PC. Peters VA Medical Center New Jersey VA Health Care SystemīACKGROUND: The utility of penile prostheses (PPs) is proven for patients with medically refractory erectile dysfunction, even in those who have been previously irradiated to the prostate/pelvic region for prostate cancer (PC) (J Urol. ![]()
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